Search on: SEROTONIN UPTAKE INHIBITORS 
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Descriptor English:   Serotonin Uptake Inhibitors 
Descriptor Spanish:   Inhibidores de Captación de Serotonina 
Descriptor Portuguese:   Inibidores de Captação de Serotonina 
Synonyms English:   Serotonin Reuptake Inhibitors
5-Hydroxytryptamine Uptake Inhibitors
5-HT Uptake Inhibitors  
Tree Number:   D27.505.519.625.600.850
D27.505.519.625.850.900
D27.505.696.577.600.850
D27.505.696.577.850.900
Definition English:   Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here. 
Indexing Annotation English:   GEN or unspecified; prefer specifics; do not confuse with SEROTONIN ANTAGONISTS; DF: SEROTONIN UPTAKE INHIB
See Related English:   Adrenergic Uptake Inhibitors
Antidepressive Agents, Second-Generation
 
History Note English:   93 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications diagnostic use
economics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects supply & distribution
standards toxicity
therapeutic use urine
Record Number:   30515 
Unique Identifier:   D017367 

Occurrence in VHL:
 

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